Department of Polymers of Medical Appointment
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The main achievements of Department

   The theoretical principles of creation of hydrophilic polymer systems for the directional transport of medicinal in an organism are designed.

   The synthesis and chemical modification of urethane-containing polymers by biologically active compounds is offered and their potential role is studied as polymers of medical using.

   The methods of creation of hydrophilic and hydrophobic polymer matrixes on the basis of polyurethanes, poly-N-vinyl pyrrolidone both hydrogels as endogenic and exogenic carriers of medicinal preparations are scientifically justified.

   The reversion mechanisms of a tumour tissue under local influencing of differentiation inductors of a tumour tissue are established.

   Established mechanisms of influencing biologically active ceramics in a structure of polyurethanes on processes of an osteosynthesis of an osteal tissue.

By results of basic researches are designed:

• Anti-tumour glue "LEVKIN" with immunomodulating properties for treatment of pathologies of soft and osteal tissues;
• High-performance anti-burns covers and medical Emplastrums for treatment of wounds and combustions, which one stimulating of tissue regeneration processes and have the broad spectrum of antimicrobial operating.
• Biological -- active compositions with bioceramics for replacement of an osteal tissue defects and for manufacturing metal – polymeric endoprosthesis;
• Antiseptic hydrophilic stuffs for manufacturing of catheters and ventings for band-pass surgery.
• Polymer stuffs for manufacturing of shells hydrophilic endoprosthesis for plastics of mammas.

Perspective scientific problems

   Synthesis of polyurethanes of a different molecular mass and hydrophylic natures, both linear, and cross-linked, which one have adjustable density of a cross-link, obtainings of polymer mixes on the basis of polyurethanes, hydrophylic oligomers and polymers, hydrogels and medicinal preparations, detail analysis of influencing of an intermolecular interaction of medicinal preparations and polymer on diffusion of medicinal in polymeric, time and speed of their release, chemical modification of polymer stuffs.

   As a result of the conducted researches the extending principles of regulation of a biological activity of urethane-containing polymers will be formulated.

Perspective development

1. 1. NEW POLYMER DRUGS WITH PROLONGED MEDICAL OPERATING ALCHOCOLISM AND DRUG ADDICTION FOR PREVENTIVE MAINTENANCE OF TREATMENT.

2. 2. POLYMER COMPOSITE MATERIALS WITH MEDICAL PROPERTIES FOR BRAIN FIRM SHELL PLASTICS, CLOSING TREPANATION FORAMENS, OSTEAL WRECKAGES FIXATION.

3. 3. ANTI-MYCOTIC POLYMER DRUGS.

4. 4. POLYMER DRUGS - INHIBITORS OF AN ANGIOGENESIS.